Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/296061485?client_source=feed&format=rss
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Wednesday, April 3, 2013
Tuesday, April 2, 2013
Access to mental health care lacking for children, teens across the U.S.
Apr. 2, 2013 ? Everyday, news reports detail the impact of the deficiencies in the nation's mental health care services. Even more startling, a survey from the University of Michigan reveals that many adults across the U.S. believe children and teens have extremely limited or no access to appropriate mental health care services.
The W.K. Kellogg Foundation commissioned the National Voices Project to facilitate a five year study to gauge opportunities available for children and teens at the local level in communities across the U.S. Officials at the National Voices Project based their study on the perceptions held by adults who work and volunteer on behalf of children day-to-day.
"The adults in the National Voices Project survey work or volunteer on behalf of kids. These are the adults who are perhaps best positioned to refer children and teens to the healthcare services they need," says Matthew M. Davis, M.D., M.A.P.P., director of the National Voices Project, associate professor of Pediatrics and Communicable Diseases at the University of Michigan Medical School and associate professor of Public Policy at the Gerald R. Ford School of Public Policy.
Survey participants were asked how much availability there is in their communities for children and teens to receive healthcare services. More than half of all respondents note that there is "lots of availability" for teens to have hospital care (55%) and primary care (56%) in their communities, but across all healthcare services, only 30% of respondents reported "lots of availability" for mental health care. Healthcare availability for children was very similar.
"These findings indicate low availability of mental health care for children and teens in the majority of communities across the U.S.," says Davis. "Even in communities where there are lots of opportunities for children and teens to get primary care or hospital care, access to mental health care is lacking."
In addition, in communities where respondents perceived racial/ethnic inequities, they consistently reported less access to all healthcare services, including mental health, especially for teens.
The full survey shows that where there are perceived inequities at the community level there are also perceptions of diminished opportunities for young children and teens in the domains of nutrition, health, and healthcare.
To read the full report, please visit: http://nationalvoicesproject.org/america-healing-grantees/resource-center/disparities-access-healthcare-teens
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The above story is reprinted from materials provided by University of Michigan Health System.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/4_7B31WXt2E/130402143946.htm
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New drug target companion prognostic test for hormone therapy resistance
Apr. 1, 2013 ? A team of international cancer researchers led by Dr. Mathieu Lupien at the Princess Margaret Cancer Centre, University Health Network, has identified the signalling pathway that is over-activated in estrogen receptor (ER)-positive breast cancer cells that are resistant to hormone therapies such as tamoxifen, aromatase inhibitors or fulvestrant.
Resistance to hormone therapy is reported in almost half of ER-positive breast cancer patients and no cure is currently available. The fact that the pathway, called Notch, is a drug target creates hope for a new therapy.
The findings, published online today in the Proceedings of the National Academy of Sciences, "provide a new therapeutic target against hormone therapy-resistant breast cancers and a companion test to identify tumours that would become resistant" says Dr. Lupien, a scientist at the Ontario Cancer Institute, the research arm of the cancer centre, and an Assistant Professor in the Department of Medial Biophysics, University of Toronto. He specializes in epigenetics of hormone-dependent cancers -- the study of non-genetic determinants of cellular identity that can also be altered to initiate or modify disease.
"In studying the epigenetics of hormone therapy resistance, we discovered that breast cancer cells behave like a chameleon. Indeed, as the chameleon changes its skin colour to camouflage itself and evade predators," says Dr. Lupien, "breast cancer cells change the appearance of their DNA through epigenetics to evade, in this case, hormone therapy." In so doing, hormone therapy-resistant breast cancer cells highlight regions of their DNA related to the Notch pathway.
At the molecular level, the research team characterized the epigenetic appearances of the DNA of drug-resistant and drug-responsive breast cancer cells. The team discovered that the Notch signaling pathway plays the predominant role in drug-resistant breast cancer cells even if cells remain positive for ER.
"This is a highly promising discovery that could rapidly translate in the clinic. Drugs against the Notch pathway are available." says Dr. Lupien. The key will be to test the efficacy of these drugs against hormone therapy resistance in breast cancer.
The research was funded by the National Cancer Institute, the American Cancer Society and the Ontario Institute for Cancer Research. Dr. Lupien's research is also supported by The Princess Margaret Cancer Foundation.
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The above story is reprinted from materials provided by University Health Network.
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Journal Reference:
- Luca Magnani, Alexander Stoeck, Xiaoyang Zhang, Andr?s L?nczky, Anne C. Mirabella, Tian-Li Wang, Bal?zs Gyorffy, and Mathieu Lupien. Genome-wide reprogramming of the chromatin landscape underlies endocrine therapy resistance in breast cancer. Proceedings of the National Academy of Sciences, 2013; DOI: 10.1073/pnas.1219992110
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/pUzj0i7pl44/130401151035.htm
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A Tiny Wacom Stylus Is a Perfect Phone Companion (If You Don't Lose It)
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First family takes part in White House Easter Egg Roll
By Gabriel Debenedetti
WASHINGTON (Reuters) - Sometimes being president of the United States isn't just about being in command. There is also the rare opportunity to shed the heavy concerns - and the necktie - and spend time with citizens focused more on food and fun than power and politics.
Barack Obama escaped briefly from North Korean tensions and Capitol Hill battles to spend time with the Easter Bunny and 30,000 visitors on the south lawn of the White House for the 135th annual Easter Egg Roll on Monday morning.
The first family walked amid the pastel-clad crowd, taking part in the egg rolling, sports, cooking stations and story telling, as part of the tradition, which dates back to President Rutherford B. Hayes.
"You guys brought the great weather. It was a little shaky this morning, but all of you did a great job sending a message upstairs, and now we've got beautiful weather," the president told the visitors at the beginning of the event.
Michelle Obama then took over in welcoming the crowd, encouraging the children in the audience to "eat your vegetables, OK?"
She said the event was held "in celebration of nutrition and health and activity."
The First Lady regularly advocates healthy eating and fitness, and continued to do so with the crowds of visitors and performers in costume.
Among the visitors were families from Newtown, Connecticut, the site of a December school shooting that left 27 people including 20 young children dead.
The president went to the egg rolling station before heading to play basketball. At the basketball court, he made just two of 22 shots. He was joined by members of the National Basketball Association's Washington Wizards.
Michelle Obama spent part of the morning with NBC weather forecaster Al Roker and chef Anne Burrell at a cooking station, where they prepared pasta.
She then met up with her daughters, Sasha and Malia, and the first family's dog, Bo, for a reading of two children's books, including "Cloudy With a Chance of Meatballs."
The White House hosted celebrities in addition to the Wizards players, including NASCAR driver Danica Patrick and singer Jordin Sparks.
(Reporting by Gabriel Debenedetti; Editing by Cynthia Johnston, Scott Malone, Jackie Frank and Steve Orlofsky)
Source: http://news.yahoo.com/first-family-takes-part-traditional-white-house-easter-180251421.html
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Okla. board pushes for charges against dentist
TULSA, Okla. (AP) ? Citing the scope of a public health scare involving thousands of patients of an Oklahoma oral surgeon, the head of the state's dentistry board said Monday she wants prosecutors to consider pursuing criminal charges.
Nearly 1,000 of Dr. W. Scott Harrington's 7,000 patients have now been tested in Tulsa for hepatitis B and C as well as HIV, the virus that causes AIDS. About 400 people showed up at a clinic north of downtown Saturday, the first day the free tests were offered, and nearly 560 people showed up Monday.
Susan Rogers, the executive director of the Oklahoma Board of Dentistry, told The Associated Press that she talked with Tulsa County District Attorney Tim Harris on Monday to discuss whether Harrington is criminally liable.
"We're looking for the witnesses and individuals who can testify for us that this is what happened to me in (Harrington's) office," Rogers told AP.
The 17-count complaint filed last week by Rogers' office called Harrington a "menace to the public health." The complaint also said officials found rusty instruments, potentially contaminated drug vials and improper use of a machine designed to sterilize tools at Harrington's two Tulsa-area offices.
Harrington and his staff could face at least two felony charges, Rogers said, including practicing dentistry without a license and aiding or abetting another person who is violating the state's dental act. Rogers said each possible charge could carry a prison term of up to four years and a $10,000 fine.
"I did speak to the DA this morning and I've talked to other officials, and I can't comment on those conversations, but there's more to come," Rogers said.
A spokeswoman at the district attorney's office could not comment Monday because prosecutors haven't received any paperwork from the dentistry board. A message left Monday morning with Harrington's attorney in Tulsa was not immediately returned.
Harrington had been a dentist for 36 years before voluntarily giving up his license March 20. He faces an April 19 hearing at which he could have his certification revoked.
Letters have been sent to 7,000 patients, urging them to be screened for hepatitis B and C and the virus that causes AIDS. Those letters should arrive no later than about two weeks, Kaitlin Snider, spokeswoman for the Tulsa Health Department, said Monday.
"We are here for the long haul," Snider said. "We know we can't screen 7,000 patients in a day or even in a week."
Those who have been tested should receive their results within two weeks, she added.
According to the Oklahoma Dentistry Board's complaint, Harrington's practice had varying cleaning procedures for its equipment, needles were re-inserted in drug vials after their initial use and drug vials were used on multiple patients.
Also, dental assistants performed some tasks reserved to a licensed dentist, such as administering IV sedation. A device used to sterilize equipment hadn't undergone required monthly tests in at least six years.
"When this started, I had no idea it was going to be this bad or this broad," Rogers said Monday. "This one scared me."
The public alert began after a patient of Harrington's initially tested positive for HIV in a screening at a third-party provider. But more testing indicated that the patient was not positive for HIV, only hepatitis C, the Tulsa Health Department said Friday.
Court records show that Harrington was sued for medical malpractice in 1994, and the case was settled in 1995. He also was sued for negligence in 1997, which was settled out of court in the same year.
Source: http://news.yahoo.com/okla-board-pushes-charges-against-dentist-211445501.html
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Monday, April 1, 2013
The importance of minimum viable products and user focus
Michael Jurewitz, former developer tools evangelist at Apple, has been blogging up a storm this week, with two great pieces on two important subjects for developers. First is the idea of minimal viable products, or how much you need to build in order to be able to start selling your current work, and supporting your future work. Jury says:
You need to get your product out the door and into your user's hands. The very act of someone touching and using your product will inherently change what you think you know about it and how you envision people using it. You will change your mind, you will change your plans, and things you used to think were important will melt away and be replaced by other needs and priorities. Having real users is a formative event for a product and one you shouldn't artificially delay.
The second, not unrelated topic is user focus, or understanding how your product will provide a delightful user experience before you type character one on code. Jury again:
Focus on the user. Focus on their life, their problems, and how you are helping them. Put down that database, put down that web server, put down that Core Data model and think. No, this step doesn't involve code. Yes, for many of you this will feel foreign and scary, but focusing on the user is liberating. It frees you from your technical shackles and puts the world in real perspective. Your focus becomes the things that matter, the things that change people's lives. Technology is a hindrance when it doesn't get out of the way. Technology is a hindrance when it becomes the point, as opposed to the human experiences we are trying to improve.
Back in a past life, when I was working in product marketing, I used to think of roadmaps like season arcs of Buffy the Vampire Slayer. I'd seen how Joss Whedon would graph out major character moments and beats on a white board, and I wanted that same sense of story, of major plot points, and of epic final releases that he brought to television.
In entertainment, you have to grab the audience. In software, you have to grab the user. Each major point release has to have something interesting in it, and it all has to build to the next major version number.
You can't and shouldn't blow the whole story in the first episode, and you can't and shouldn't blow all your features in a 1.0 release. You should create interest and get the job done, absolutely, but you should also leave people wanting more. And you should know how your next act, your 2.0 is going to premiere, and build towards it. (That's also how you attract and maintain press attention for your products, of course, because we're simply an extension of audience.)
Go read Jury's articles, then go make some more great stuff.
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Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/933Y90zWoDo/story01.htm
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